acitretin
Print| Trade Name(s): Acitretin; Soriatane | |
| Group 3: Reproductive Hazard | AHFS Class: Keratolytic Agents |
| Formweb: acitretin | |
| Info Links: Chemotherapy Extravasation Policy | |
Disposal:
demo-disposal icons
| ICONS | DESCRIPTION |
 | Black bin |
 | Blue bin |
 | Green bin |
 | Purple top bin |
 | Red (sharps) bin |
 | Yellow bin |
 | Trash |
 | Controlled Substance (CsRx) bin |
 | Controlled Substance (Cactus) bin |
 | Spill kit |
Black Box Warning:
PPE:
demo-PPE ICONS
| ICON | DESCRIPTION |
 | Gloves (single layer) |
 | Gloves (double layer) |
 | Gown |
 | Hair Cover |
 | Shoe cover (single layer) |
 | Shoe cover (double layer) |
 | Goggles |
 | Face shield |
 | N95 Mask |
 | Surgical mask |
| Hair cover |
 | Full Face Respirator |
 | Powered air purifying respirator |
 | Coverall (Bunny suit) |
Mechanism of Action:
The mechanism of action of acitretin is unknown, however it is believed to work by targeting specific receptors (retinoid receptors such as RXR and RAR) in the skin which help normalize the growth cycle of skin cells.
Reference: Drug Bank
Exposure Risk:
- Causes skin irritation.
- Causes serious eye irritation.
- May damage fertility or the unborn child.
- Very toxic to aquatic life.
- Very toxic to aquatic life with long lasting effects.
Reference: SDS - Cayman Chemical
Safety Data Sheet(s):
Supplemental Information:
NIOSH 2016: "Black Box warning on adverse reproductive effects"
NIOSH 2020: "Only met the NIOSH criteria as a developmental and/or reproductive hazard"
Approved on September 12, 2024
