acitretin

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Trade Name(s): Acitretin; Soriatane
Group 3: Reproductive Hazard AHFS Class: Keratolytic Agents
Formweb: acitretin
Info Links: Chemotherapy Extravasation Policy
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Mechanism of Action:

The mechanism of action of acitretin is unknown, however it is believed to work by targeting specific receptors (retinoid receptors such as RXR and RAR) in the skin which help normalize the growth cycle of skin cells.

Reference: Drug Bank

Exposure Risk:

  • Causes skin irritation. 
  • Causes serious eye irritation. 
  • May damage fertility or the unborn child. 
  • Environmental hazards

Reference: PubChem

Supplemental Information:

Only met the NIOSH criteria as a developmental and/or reproductive hazard

Approved on November 22, 2024