nirogacestat
Print| Trade Name(s): Ogsiveo | |
| Group 0: N/A | AHFS Class: Antineoplastic Agents |
| Formweb: nirogacestat | |
| Info Links: Chemotherapy Extravasation Policy | |
Mechanism of Action:
Nirogacestat is a gamma secretase inhibitor that blocks proteolytic activation of the Notch receptor. When dysregulated, Notch can activate pathways that contribute to tumor growth.
Reference: DailyMed
Exposure Risk:
- Hazard statement(s)
- Harmful if swallowed
- Causes skin irritation
- Causes serious eye irritation
- May cause respiratory irritation
Reference: PubChem
Safety Data Sheet(s):
Approved on November 22, 2024
